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BMC Genomics 24 , 232 (2023)

Rajput VD, Harish SRK, Verma KK, Sharma L, Quiroz-Figueroa FR, Meena M, Gour VS, Minkina T, Sushkova S, Saglara M

Endothelial dysfunction and prothrombotic reprogramming Endothelial cells (ECs) exposed to NET components undergo profound functional reprogramming, shifting from physiological vascular homeostasis toward inflammationdriven endothelial injury and a procoagulant phenotype [78]

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Following this, there have been two clinical phase 2 trials (SAR425899 and MEDI0382 also known as cotadutide) published evaluating GLP-1/glucagon receptor co-agonists