COPD involves significant mitochondrial alterations such as reduced oxidative phosphorylation (OXPHOS) and mitochondrial fragmentation
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Symptoms that improve may include: Shortness of breath Chest tightness or pain with exercise or other movement Unusual weakness with exercise Leg pain with exercise Numbness, tingling, or weakness in an arm, leg, or face In people who stop smoking and also treat some of the other risk factors (exercise, healthy weight) blocked arteries can get better
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