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However, one animal study has demonstrated that e-cigarette vapours can cause DNA changes in rat models which is the mechanism through which cancer develops. And even though the main cancer-causing chemicals (like tar) of tobacco smoke are absent in e-cigarettes, many other carcinogenic particles are still present

"Question in the Form of An Answer: An Interview With Mac DeMarco"

doi:10.1111/j.1530-0277.1997.tb04511.x

Theres also evidence that people who smoke while getting cancer treatment have a worse outcome (prognosis), are less likely to respond to treatment and are more likely to have the cancer come back (recur)