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PMID 29459389

ND heritability is enriched for genes expressed in cerebellum To assess whether heritability of ND is enriched in regions surrounding genes with the highest specific expression patterns in given tissue/cell type(s), we applied LDSC-SEG 44 using the EUR-specific ND GWAS meta-analysis results with reference to 205 tissues/cell types with publicly available gene expression data assembled from GTEx 45 (53 human tissues/cell types) and the underlying data that is used to comprise the Data-driven Expression Prioritized Integration for Complex Traits (DEPICT) tool 46,47 (152 tissues/cell types from humans and rodent models)

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Spencer, offered this remembrance: The symposium had two significant outcomes