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These effects were mediated by the 5-HT4 receptor and associated with an increase in cAMP (cyclic adenosine monophosphate) content and the subsequent elevation of the phosphorylation state of Ca 2+ regulatory proteins [67]

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Replacing one source of nicotine with another can maintain dependence

The device is unique in that it converts chemicals into their metabolites during testing, which replicates what happens in the human body, Kadimisetty says

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