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Tobacco use weakens the lower esophageal sphincter, increases stomach acid production, and impairs the esophaguss natural ability to clear acid, creating a perfect storm for persistent and worsening reflux symptoms

Aging and Skin Damage: Tobacco use accelerates the aging process, leading to premature wrinkles, sagging skin, and a dull complexion

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IOSR J Agric Vet Sci 7:3540 Owoeye JA, Akawa OB, Akinneye JO, Oladipupo SO, Akomolede OE (2016) Toxicity of three tropical plants to mosquito larvae, pupae and adults