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It was investigated as a candidate obesity therapeutic but did not meet its primary endpoints in clinical trials, and no marketing approval followed

In practice, some people with B12 deficiency may be able to switch to very high dose (e.g

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You can help to regulate your mood and mental health better with a boost of vitamin b12 where there is a natural increase in levels of mood-regulating brain chemicals such as serotonin and dopamine

"Vitamin B 12 in the Vegan Diet"