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ii) NADH-specific GDH The activity of both the forward and reverse NADH-GDH reactions were assayed using a combination of methods from Loyola-Vargas et al

Particularly, the significant variation in inducing conditions such as IL-1, oxidative stress, and iron load across different studies makes it unclear whether SLC7A11 downregulation is a universal mechanism in OA, lacking systematic assessment of consistency across models

Clinical evaluation: Patient history: symptoms such as weight changes, energy levels, temperature sensitivity, and emotional well-being can provide clues

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