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That's the day implementation of Minnesota's newest tax -- aimed at reducing cigarette smoking, counteracting tobacco marketing campaigns and improving the overall health of its citizens -- begins

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A separate study also found protein levels of IL-6 and IL-8 to be increased in co-cultured primary gingival epithelial cells and fibroblasts in response nicotine-containing e-cigarette exposure and MCP-1 and TNF protein concentrations to be elevated independent of nicotine content (90)