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Doses may need to be higher in heavy smokers or heavy drinkers

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In essence, a luxury cigarette is the difference between a regular cup of coffee and a single-origin, hand-poured, barista-crafted espresso

And it increases the effectiveness of health warnings." Earlier this month, France, Great Britain and Northern Ireland started implementing requirements for the packages, and leaders in Ireland also plan to introduce it

However, the researchers noted that the study had several limitations to be considered including that the meta-analysis was based on observational studies, that PNE had the potential to be misclassified due to most of the studies being based on self-reported data, and that there was high statistical heterogeneity across the studies