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lung.org , (2019)

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However, animal research has also found that estrogen enhances dopamine release in the striatum and nucleus accumbens in the absence of drug exposure [26]it is therefore possible that estradiol may attenuate smoking cravings and reward by enhancing basal dopamine transmission

This all comes as the FDA is opening a criminal probe into 530 cases of hospitalizations related to vaping, and the state health department is asking people who vape to complete an anonymous survey