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It reduced the levels of pSTAT-3 and p-AKT in those cells, resulting in lower expression of pro inflammatory cytokines

Cells were pelleted by centrifugation at 3,500 g for 35 min at 4C, resuspended in 100 mL of 50 mM KPi and 100 mM NaCl, pH 7.4

GTPase signaling Guanosine triphosphatases (GTPases) are a group of enzymes that hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP) and inorganic phosphate

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Following the elevated FSH level, the antral follicles produce inhibin and estrogen, with negative feedback on FSH