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Signs of nicotine poisoning in cats can appear rapidly (15-60 mins) and include: Vomiting and/or diarrhea Excessive drooling Agitation, restlessness, or hyperactivity Increased heart rate and breathing rate Tremors or muscle twitching Incoordination (ataxia) Lethargy or collapse Seizures If you suspect your cat has ingested e-liquid or any part of a vape device, it is a critical emergency