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Protocol which included baseline recording, 16 water swallows (5 ml, 10 ml, and 15 ml) and the multiple rapid swallows was performed before and after esophageal infusion of menthol (3 mM, 20 min, 8 ml/min)

Where and how to sign All citizens of legal age can sign, by going to the Ministry of Justice platform (click here) and using their Spid, Cie (Electronic Identity Card) or Cns (National Services Card)

Nicotine acts as a potent stimulant that affects the central nervous system, creating a cycle of craving and relief that makes cessation extremely difficult for regular users