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On September 9, 2020, Black Buffalo submitted a bundled PMTA for its five long cut and three pouches smokeless tobacco alternative nicotine-containing products, marking a substantial milestone in the Company's history and ensuring the aforementioned products' continued marketing during the PMTA review process

These findings should be interpreted with caution because this was a very short-term investigation (only 6 weeks), and the authors of that research had connections with nicotine pouch manufacturers [53]

5 is a graph showing isothermal adsorption and desorption characteristics of the cigarette paper according to an embodiment of the present invention