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The Harm Reductionists: An Alternative to Quit or Die Harm reduction is simple in concept but controversial in practice

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are using cannabis more frequently now, with 18 million people using cannabis on a daily or near-daily basis in 2022, which is twenty times higher than in 1979

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We applied locally weighted polynomial regression (Loess) with varying smoothing spans (0.3, 0.4, 0.5) to generate smoothed frontier lines that capture the nonlinear SDIASDR relationship