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CSE exposure increased MKK3 expression and was accompanied by enhanced p38 MAPK phosphorylation and PRKN Ser131 phosphorylation, together with reduced PRKN/PINK1-related mitophagy readouts and increased senescence markers

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Perhaps most distressing, clients will experience the same kind of craving for nicotine, as they do for alcohol indeed, the same kind of craving that they tried to smooth over with cigarettes in the first place