This, in turn, activates the cGAS-STING pathway, leading to the upregulation of cGAS-STING-dependent inflammatory cytokine expression 25) ( Fig.2 )
A study enrolling 504 patients found that all forms of NRT evaluated (gum, patch, nasal spray, and inhaler) produced similar quit rates and were equally effective at reducing the frequency, duration, and severity of urges to smoke [41]
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