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[69] Menthol cigarettes have been shown to inhibit nicotine metabolization, leading to increased systemic nicotine exposure and increased nicotine addiction

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In Western countries, about three times as many men as women suffer from alcohol misuse and dependence, but in Asian and Hispanic cultures a higher ratio of men to women are affected

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Free Black and immigrant day laborers formed the core of the labor force, supplemented by significantly smaller numbers of enslaved people in these regions