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It was also observed that prenatal secondhand smoke significantly elevated the secretion of Th2 cytokines, including IL-4 and IL-13, and promoted activation and polarization of Th2 cells and pulmonary inflammation in BALB/C mice [50, 51]

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TMV is a virus that is commonly found in tobacco plants which causes splotchy or twisted leaves, strange mottling symptoms (a mosaic), slowed growth, and reduced yields

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