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Despite the preliminary evidence presented earlier, the potential adverse effects of aerosols, nicotine, and other ENDS components on cardiac function are yet to be evaluated

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In a murine model of intratracheal LPS-induced pulmonary inflammation, treatment with adenosine or NECA (5'-N-ethylcarboxamidoadenosinenon-selective AR agonist), resulted in a decrease in inflammatory response and improvement of barrier function, as seen by decreased cell counts, Evans blue dye albumin (EBDA) extravasation, protein and cytokine levels, and reduced neutrophil infiltration

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