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In terms of safety, theres basically no difference, according to research from Stanford University: the fact that the tobacco in these cigarettes was grown without genetic modification or fertilizers doesnt negate the fact that theyre, you know, still cigarettes

The withdrawal symptoms are uncomfortable, and when you start feeling bad from withdrawal you can get rid of it in ten seconds by taking a drag on a cigarette

Its obviously going to get warmer over night, but if you don't open it etc it may maintain temp to an acceptable level