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This is supported by the relative bioavailablity of nicotine from the NPs used in this study, which showed that Zyn had the lowest level, followed by Skruf, Lyft, Nordic Spirit and On!, with the latter three products having relative bioavailabilities ranging from 1.37 to 2.45 times higher than Zyn

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With smokeless tobacco products, the product is kept in close contact with the mucosal lining of the mouth for long durations, resulting in sustained chemical absorption

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Hennekens also highlighted the urgent need for targeted interventions, especially considering the differing health risks associated with teen cigarette smoking