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Neuroinflammation and blood-brain barrier disruption following traumatic brain injury: pathophysiology and potential therapeutic targets

Individual peptide monotherapy groups and BPC-157 alone and TB-500 alone at the same doses used in the combination group and are essential for determining whether combination effects are additive, synergistic, or less than additive relative to each individual peptide

Intramuscular (IM) vitamin injections are administered directly into the muscle

Methods 11 , 783784 (2014)

Second, crossing Jnk1 LoxP/LoxP / Jnk2 -/- mice with Alb-Cre mice deletes Jnk1 in hepatocytes during embryogenesis, raising the possibility of compensatory gene induction that could interfere with the final outcome