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Animal studies have explored its effects on gastric ulcer models, inflammatory bowel conditions, and intestinal anastomosis healing, with researchers observing notable cytoprotective responses in mucosal tissue models

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It also supports respiratory health by thinning mucus, which is relevant for those detoxifying from cigarette smoke exposure

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This enzyme is encoded by a single gene in Arabidopsis (At5g43940), and catalyzes the NADH-dependent reduction of GSNO to S -aminoglutathione, which then decomposes to ammonia and free GSH (Sakamoto et al., 2002