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Furthermore, nicotine enhances the formation of the N-methyl-D-aspartate receptor/neuronal nitric oxide synthase/postsynaptic density protein-95 complex, promoting calcium influx, nitric oxide production and downstream p38 MAPK phosphorylation, mechanisms that contribute to excitotoxic neuronal damage, and deficits in learning and social behavior (18)

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Once initial testing is completed and prior to deployment, the application will undergo appropriate review by the California Department of Technology

These data suggest that cigarette smoking may provoke harmful changes in the ILC3 subset in the asthmatic airways