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Some key biological causes include: Neurochemical Changes: Nicotine, the primary psychoactive component of tobacco, interacts with nicotinic acetylcholine receptors in the brain, leading to the release of neurotransmitters such as dopamine, as discussed by Berrendero, F

Heated tobacco devices, also known as heat-not-burn devices, heat real tobacco within a specific temperature range, using an electronic heat-control system to prevent it from burning

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In combination with medication-assisted treatment or as a standalone treatment, these behavioral therapies are valuable tools in helping individuals overcome substance use disorders and maintain long-term recovery

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