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Relevant when hemorrhoidal flare-ups coincide with systemic immune dysregulation

In medical settings, it may also be used to support liver function and boost immunity

Becker KG, Schultz ST

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We know that not only can the brain be a target of the peripheral immune system, but also that the organ itself is home to a broad and diffuse immune system, present in the meningeal membranes, choroid plexus, cerebrospinal fluid and even directly in the brain parenchyma [49,50]