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At the time, tobacco smoking was already well established across Europe, primarily through pipes and cigars

Under REMS, prescribers were required to monitor absolute neutrophil counts (ANC) weekly for the first six months, then every two weeks for another six months, and monthly thereafter ( DellOsso et al., 2024 )

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We'll see why this is and where it all began

Cool, Dark Storage: Protects against light and heat, maintaining potency