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Dec 28 2005;294(24):3101-3107

doi: 10.3390/md9020278 12 PanyakampolJCheevadhanarakSSutheeworapongSChaijaruwanichJSenachakJSiangdungWet al

If osmotic and stool-softening options prove insufficient, discuss prescription options like linaclotide (Linzess) or plecanatide (Trulance) with your healthcare providerthese are gut-selective agents that may be safer in GLP-1 users than older stimulants

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Research protocols should run a minimum of 8 weeks to capture both the acute GH response and the secondary anabolic cascade (IGF-1 elevation, nitrogen retention, lipolysis markers)