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It also contains phenols responsible for the unpleasant taste and throat irritation, aldehydes (formaldehyde, acrolein) toxic to the cilia of the respiratory epithelium, and heavy metals absorbed by plants from the soil (cadmium, lead, chromium)

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Levels of preformed NNN and NAT, B (a) P, and nicotine in aqueous extracts of black and brown masheri were higher than in tobacco used for their preparation.[] HCN and phenols shown to have tumor promoting and co-carcinogenic activities were detected in both brown and black masheri

Given these great truths, Publius argued that the best hope for stopping war among the American states was to unite them under the proposed federal constitution

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