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Additionally, those expecting drastic or permanent skin color changes should be properly informed about the realistic limitations of this approach

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Accordingly, drug-mediated regulation of Wnt/-catenin signalling activity to induce liver regeneration would benefit this group of patients based on the key role of Wnt/-catenin signalling in the pathobiology of non-tumour diseases such as steatohepatitis, 78,310 cholestasis, 311 and liver fibrosis

Early animal studies showed promising results, with obese mice losing significant body fat without changes in food intake or lean muscle mass