Methamphetamine addiction is prevalent in many countries, with an estimated 27 million people using methamphetamine globally in 2019, according to the United Nations Office on Drugs and Crime (UNODC)
Plain packaging will reduce the appeal of tobacco packages and brands
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In animal studies, prophylactic administration of phenobarbital, but not phenytoin, has been shown to delay the onset of theophylline-induced generalized seizures and to increase the dose of theophylline required to induce seizures (i.e., markedly increases the LD 50)
Individuals may experience fatigue, depression, anxiety, irritability, and intense cravings for the drug