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6 The more frequent and greater the consumption of these, the larger the risk is Alcohol: excessive alcohol is harmful, but a combination of alcohol and tobacco presents the highest risk Medical history: We need to pay attention to our patients' medical history as evidence suggests that both the Human Immunodeficiency Virus (HIV) and Human Papilloma virus (HPV) (especially types 16 and 18) infections may increase the risk of lip cancer

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