Analysis of protein profiling studies of beta-thalassemia/Hb E disease
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Additionally, keratinocytes and Langerhans cells (LCs), release cytokines such as IL-10, IL-12, IL-18, IL-23, IL-17 and IL-22 and thymic stromal lymphopoietin (TSLP), leading to an enhanced Th2-type inflammatory response (48, 50, 51)
One of the main factors leading to the development of these diseases is the overproduction of ROS, together with the reduced bioavailability of nitric oxide (NO)
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