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A large body of evidence showed that direct skin exposure to cigarette smoke containing a large number of oxidants and radical species 40 leads to lipid peroxidation 41 associated with the skin barrier impairment demonstrated by the increased TEWL in various experimental models 5, 6 as well as in the cheek of smokers 4

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titled Prescription Psychostimulants for the Treatment of Amphetamine-Type Stimulant Use Disorder, published in Addiction (2023), treatment approaches to stimulant addiction include behavioral therapy, medication-assisted treatment, and detox programs to address both psychological and physical dependencies