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However, these challenges spurred innovation and led to groundbreaking advancements in the industry

As shown in Figure 4, the serum cotinine level in mice exposed to tobacco smoke for 12 weeks is 3.1-fold higher than those exposed to room air for the same period and the serum cotinine level in mice exposed to tobacco smoke for 24 weeks is 4.8-fold higher than those exposed to room air for the same period

5 Preventive measures are likely responsible for the significant decline in non-fire-related CO poisoning deaths from the early 1970s through the 1990s

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Brookline became the first U.S