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In laboratory studies, the maximum plasma nicotine concentration levels with first-generation devices ranged from 1.3 to 5.36 ng/ml five to 24 minutes after use, depending on the nicotine concentration of the e-liquid [912]

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This might be because public regulations significantly limit smoking opportunities and time for smokers in specific places, such as restaurants, bars, and offices

Adopt or revise comprehensive agricultural labor policies to protect the health, safety, and human rights of workers employed on tobacco farms, in line with international law and the United Nations Guiding Principles on Business and Human Rights

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