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It occurs when the bodys immune system mistakenly attacks and destroys melanocytes

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Similarly, berberine, an isoquinoline alkaloid, has shown profound regulatory effects on gut microbiota in multiple experimental models of GI inflammation

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Notably, this process functions independently of endogenous growth hormone-releasing hormones (GHRH), providing an alternative pathway for inducing growth hormone release

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doi: 10.1371/journal.pone.0186802

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