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Growing astronomically from its first year in 1966 from $3 billion to $524 billion in 2010, expenditures represented 15 percent of all federal outlays and 3.7% of the gross domestic product

The maximum dose can be continued for eight to 12 weeks and tapered down at the end to avoid withdrawal symptoms that may occur if it is stopped abruptly

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For results based on the sample of 832 nonsmokers, the maximum margin of sampling error is 4 percentage points