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Fertility studies performed in male and female rats at oral doses of ciprofloxacin up to 100 mg/kg (approximately 0.6-times the highest recommended therapeutic oral dose based upon body surface area) revealed no evidence of impairment

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Smoker preference surveys indicate Marlboro leads for sheer intensity (favoured by 65%), while 555 is preferred for superior smoothness and a cleaner throat hit (favoured by 55%)