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Conclusions In conclusion, Cytobacillus oceanisediminis C4 and Bacillus subtilis B1 isolated from tobacco could play a key role in the fermentation process of different tobacco morphologies (TP and TL) by regulating chemical composition, improving aroma components, and changing tobacco surface structure and tobacco microbiota

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Lower -opioid receptor BP was also detected during the denicotinized smoking condition in the smoker group, compared to baseline scans in non-smokers, in the cingulate cortex, thalamus, ventral basal ganglia, and amygdala