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AV occurs in early life and presents with erythema and follicular, keratotic papules leading to a symmetrical honeycomb-like pattern of atrophic scars on the cheeks, preauricular area, and remit by puberty [Figure 8]

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After 16 weeks, the methacholine challenge test showed that CS exposure affected the lung function of mice, and airway hyper-responsiveness (AHR) was elevated in a concentration-dependent manner (Fig