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Effects of Nicotine and Vaping Harmful Effects of Nicotine Harmful Effects of Vaping What Happens When You Quit Ready to Quit Step 1: Think about why you smoke or vape Understanding why you started and continue can help to prepare you for those moments you miss it and dealing with withdraw symptoms and cravings

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Cigarettes expose the body to toxins, and nicotine may boost the production of lipids that contribute to NAFLD

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Nicotine that is inhaled from tobacco smoke or alternative tobacco and nicotine products enters the blood circulatory system and rapidly crosses the blood-brain barrier 48 By binding to nicotinic acetylcholine receptors (nAChRs) in the brain and opening channels for neurotransmitters, nicotine stimulates the release of neurotransmitters, including dopamine and glutamate 49 Increased nicotine use leads to more of these receptors, increasing craving and dependency leading to even higher nicotine use 50 The use of alternative tobacco and nicotine products is likely to contribute to this increasing cycle of consumption, with sustained or increased nicotine use as the result Nicorette disrupts the cycle of higher nicotine use by providing therapeutic doses of nicotine that will reduce cravings in a dosing regimen that can be tapered down