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The synergistic effect of nutritional-related metabolic syndrome on OA Beyond obesity alone, the constellation of nutrition-related metabolic syndrome (MetS) components including insulin resistance, dyslipidemia, and hyperglycemia, synergistically exacerbates OA progression through interconnected pathways

Some of the side effects of glutathione The use of glutathione should be under expert guidance

J Hepatol 65:12451257

In addition, Nrf2 can also regulate the expression of downstream enzymes such as GST and GR, further improving the cell's antioxidant defense network and enabling cells to more effectively respond to damage caused by oxidative stress

Elevated homocysteine levels in the blood (i.e., hyperhomocysteinemia) may be a risk factor for cardiovascular disease and could also be linked to dementia and Alzheimers disease (20, 21)