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The most commonly reported listed methods were nicotine products (53.9%, 1.5 million US adults), primarily e-cigarettes used alone or in combination with other methods (40.8%, 1.2 million US adults)

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Additional large-scale evidence that can separate the effects of smoking age, duration, and intensity as well as adequately adjust for confounders is needed to ascertain the relationship between age at smoking initiation and cardiovascular diseases, which could have medical as well as social implications with regards to tobacco prevention and control measures