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Bioinformatics 24 , 27802781 (2008)

Folate deficiency during this period is associated with the development of autism spectrum disorders in children, neural tube irregularity, and brain development defects in the fetus and brain function in later life (68, 69)

This type of damage, often called cochlear synaptopathy, results from noise exposure causing a loss of synapses between cochlear hair cells and auditory nerve fibers, without affecting hair cell survival or audiometric thresholds 14

In addition, RT-qPCR analysis showed that WL-1 markedly reduced the expression of viral late gene UL27, early gene UL52, and immediate early gene UL54

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