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Still, the fact that cigarettes slipped to second place halfway through 2025 raises a question: Is this the year they are dethroned

albicans virulence is also mediated by proteolytic enzymes such as secreted aspartyl proteinases (Saps) [16, 17]

Among those with no initial reduction in week one, 43% (12/28) (95% CI: 2461) subsequently reduced their consumption, and one participant achieved full cessation

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* Reductions in levels of the 9 harmful chemicals the World Health Organization recommends to reduce in cigarette smoke, which do not include nicotine