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While its not the primary cause of diseases associated with smoking (such as lung cancer, emphysema, or cardiovascular disease), nicotine does have various health effects on its own: Nicotine is highly addictive

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One example is the emerging vaping industry, which has been met with controversy but is a clear disruption to the tobacco industry

To date there are no studies which have examined the impact smoking status has on the efficacy of tofacitinib in the treatment of UC

Qualitative tests determine the presence or absence of nicotine or cotinine, providing a simple positive or negative result