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5 Clinical implications and therapeutic targeting Tumor hypoxia and metabolic reprogramming have profound clinical implications, as they drive tumor aggressiveness, metastasis, immune evasion, and resistance to chemotherapy, radiotherapy, and targeted therapies

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The most bactericidal cathelicidin is the synthetic eCATH-1 (that is not present in vivo) with minimal inhibitory concentrations (MICs) between 3 and 12 g/mL for Gram-negative bacteria (including E